Oh, a scientist I know was a postdoc at MIT earning 40k U$ a year and she now ears 47k in Euros here, and she says she is much worse off, and we are only living in Bern which is WAY cheaper than Zurich.

And forget about two cars, one small car if you really need it I would say. Otherwise, public transport is much cheaper.

On the upside, doing research here might be easier as there is more money for research than in many EU countries; not sure about the US though.