OK, back to the OP.... well to be honest really not much has changed in the last 5 years.... certainly not road wise or local public transport wise anyway. There are probably more new houses, and the maternity hospital is brand new since then, other than that not so much! (Switzerland is not known for "embracing change"!)
I'm in the "prefer to drive" camp myself and if you currently commute on the M25 then frankly commuting by car into Basel will seem like a walk in the park. There is traffic at peak times but it's nearly always moving and usually pretty "polite" iykwim - people let you in, nobody gets stressed and I'm rarely queued up more than 5 minutes. I live in Aesch which is a great location transport-wise as it has a highway exit to the H18 - which is a better commute than on the main highway (A2? 3? I always forget) to Basel. Aesch also has a train and a tram so you are spoilt for choice if you prefer public transport - here the travel time always swung it for me - the train to Basel from here is only 9 minutes, but since I work on the opposite side of town to the SBB, you have to add onto that 20 mins on the tram to my office, and a 5 minute walk, plus changes and waiting for the next tram - door to door takes best part of an hour. In the end I can get in my car outside my front door and be at my desk in 20 minutes flat (that is if I didn't need to drop my kids!) even in peak traffic.
Forgetting about you for a second though and thinking of your wife - in a new country, not knowing anyone, not having the social network of a job and having a new baby to deal with - for her I personally would recommend not going too far out of Basel. There are a lot of groups and activities going on for new mums but they are nearly all based in Basel - for her I'd recommend finding somewhere on the tram line (any tram line really). Reinach / Aesch / Therwil / Oberwil / Binningen / Bottmingen / Allschwil - all these are good places for new mums because there are lots of other expat moms living in those areas - which gives an instant group of mom-friends. Even if you love living in the country in the UK, and are intending to integrate with Swiss life - coming here it can be very lonely in a small Swiss village (where it's less likely the neighbours will speak any English at all) when you have a baby and know nobody. Not to say it's impossible - just that I think she'd find it easier to make and meet friends if she were closer to town. You can always move somewhere further afield once your baby is a bit older and you've established a few connections.
One thing on the house hunting - do not expect to find a UK size garden. You will rarely find a house with more than a postage stamp size garden - mainly this is due to terrain - flat bits of land are few and far between and are therefore used for houses rather than wasted on gardens. If you find somewhere with a large sounding garden it will likely be vertical! To make up for that though there are fantastic parks all over the place. Also, houses are not easy to find - a lot of people (including families with kids) live in apartments, so houses are very desirable and with a lot of competition. Just to say don't rule out apartments - there are some very nice ones.
Oh, and the salary is absolutely fine.
And join the BCT (Basel Children's Trust)
www.baselchildrenstrust.ch