My partner and I have now lived in Massagno (right near the Lugano FFS station) for about two weeks, so here's my view as a newly-settled foreigner:
- I've found the people to be somewhat more reserved than in California, but I don' think they'd be out of place in the Northeastern US. Once I interact with people here, I find them to be generally as friendly as anyone else.
- We're paying about the same for our apartment in Massagno (a few hundred meters from the station) as we did for our apartment in San Diego. Some of the apartment things are a little strange to us - chiefly, only being allowed to use the washing machine 2 days per month.
- Public transit here is much better than we expect coming from the US, though people I've talked to from other areas of Switzerland say it's not as good as the other major cities.
- Food is more expensive than we're used to in the US, but not insanely so.
- We've run into occasional language issues - my office operates in English, but our administrative mothership is in Zurich so things like my retirement plan are all in German. We both speak a bit of Italian (and we're improving rapidly), and I can read it reasonably well but often "multi-lingual" documents are only in German and French, leaving Italian as the odd-language-out when dealing with large nationwide or worldwide companies. But overall we're doing pretty well in this regard; it's amazing what a small amount of Italian you need to learn to accomplish the basics, and when I've been in over my head I've found people to be quite patient with me.
- Shopping is reasonably easy - once you learn which stores you like, the only thing that takes some getting used to is the limited operating hours. I've found the selection at Migros, Coop, etc. to be quite good. Carrefour has more stuff and is somewhat cheaper, but it's a bit insane to navigate.
- Outside of my office, we've only encountered a couple of Americans/Canadians in the time we've been here. We live in a fairly large apartment building, and so far the only neighbor we've found who speaks English is Sri Lankan.
It's been a little stressful on occasion, but so far we're enjoying it and looking forward to warmer weather. (We moved from San Diego, so we're a bit spoiled in that regard.)
Anyway, that's enough rambling from me. Feel free to ask followups or PM me for more details.