Some great tips... I would definately agree with a test run for the drugs if you were to them. I it does not have the sedative effect and infact certain meds they have had when sick which people recommended for air travel makes them go the opposite way even worse for surrounding passengers.
I cant take the car seat with us but have brought one of the cares air travel restraints to try with out 2 year old. I have my sling for the baby as he will fall asleep if he is strapped on and a bit of walking up and down.
games and dvds and some drawing and lots of snacks hoping will keep them down.
I like that parents can board first as the point made earlier about luggage storage... the last easy jet plane they asked for children etc and the whole plane ran to the gate... there were no seats left and then people had to move so that my 2 year old was not forced to sit alone... Although a few rows in front would have been quite nice for me

maybe not for the passengers next to him.... Although I did get the middle seat as i had the baby and felt so bad as i had to sit inbetween 2 brothers who i could see wanted to chat but were too polite to talk over me bless em! Or maybe they just didnt want to wait the newborn I had on my lap!
Also i think if they let the children get on first you can as a non child person search them out and pick a seat far away as I know when im travelling without them I would pick the furthest seat away...