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24.11.2020, 12:56
|  | modified, reprogrammed and doctored² | | Join Date: Feb 2008 Location: La Cote
Posts: 15,998
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| | Re: Coronavirus
Some Eastern European Front News - steady decline in overall cases but. Social and medical stats math modellers are warning that if "recovered" areas are to go by, we aren't seeing a real recovery. The places with the lowest occurence now (they have gone through the 2nd wave earlier than the rest) dropped down, plateau-ed somewhere mid position and are again worsening, despite the discipline and strict measuers - lockdown, curfews, all social life stopped, outside gathering only out of emergency reasons and at 2 people. They are thinking of further loosening up but watching Prague new small but steady increase is discouraging. Permanent lockdown not possible, either. There will likely have to be new strategy. Christmas is a moot it looks like.
And - a 1600gr newborn was born in Brno faculty hospital by a c-sec performed on an unconscious mom on a ventilator machine, due to CV. Both are now home, safe and happy. Baby born CV negative.
__________________ "L'homme ne peut pas remplacer son coeur avec sa tete, ni sa tete avec ses mains." J.H. Pestalozzi “The only difference between a rut and a grave is a matter of depth.” S.P. Cadman "Imagination is more important than knowledge." A. Einstein
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24.11.2020, 13:24
|  | Only in moderation | | Join Date: Jul 2009 Location: Basel-Land
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| | Re: Coronavirus | Quote: | |  | | | Also my post was an Oxford comma joke that nobody seemed to get (or just didn't find funny ) | | | | | I just didn't see your post till now! Very good! | 
24.11.2020, 13:31
| Senior Member | | Join Date: Feb 2020 Location: Zürich
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| | Re: Coronavirus
Fairy tales about crossimmunity Natural coronavirus immunity could be TWICE as common as experts thought after Public Health England study claims millions have protective T-cells from catching similar cold viruses https://www.dailymail.co.uk/news/art...-Covid-19.html | The following 5 users would like to thank vladest for this useful post: | | 
24.11.2020, 13:34
| Forum Legend | | Join Date: Jun 2008 Location: Zurich
Posts: 7,984
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| | Re: Coronavirus | Quote: | |  | | | Fairy tales about crossimmunity Natural coronavirus immunity could be TWICE as common as experts thought after Public Health England study claims millions have protective T-cells from catching similar cold viruses https://www.dailymail.co.uk/news/art...-Covid-19.html | | | | | Let's see if the EF scientists agree | The following 6 users would like to thank k_and_e for this useful post: | | 
24.11.2020, 13:34
|  | modified, reprogrammed and doctored² | | Join Date: Feb 2008 Location: La Cote
Posts: 15,998
Groaned at 340 Times in 235 Posts
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| | Re: Coronavirus | Quote: | |  | | | Fairy tales about crossimmunity Natural coronavirus immunity could be TWICE as common as experts thought after Public Health England study claims millions have protective T-cells from catching similar cold viruses https://www.dailymail.co.uk/news/art...-Covid-19.html | | | | | I don't like DM but I really like that idea!
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24.11.2020, 13:54
| Member | | Join Date: Sep 2020 Location: In your head
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| | Re: Coronavirus | Quote: | |  | | | Also my post was an Oxford comma joke that nobody seemed to get (or just didn't find funny ) | | | | | I missed your post. Saw it on Twitter though | 
24.11.2020, 13:59
|  | Forum Veteran | | Join Date: Oct 2019 Location: Suhr, Aargau
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| | Re: Coronavirus
Well, it seems the economy is doing well during the 2nd wave/lockdown in Europe. Of course on average, some specific business are getting crushed. | Quote: |  | | | Business surveys, released earlier today, indicate this eurozone lockdown will be — in economic terms — nowhere near as painful as the spring’s. One reason is the remarkable pace at which industry has adapted to the pandemic. | | | | | https://www.ft.com/content/92013406-...f-ad629f28b40c | 
24.11.2020, 14:02
|  | Forum Veteran | | Join Date: Jan 2008 Location: Ausserschwyz
Posts: 997
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| | Re: Coronavirus | Quote: | |  | | | Fairy tales about crossimmunity Natural coronavirus immunity could be TWICE as common as experts thought after Public Health England study claims millions have protective T-cells from catching similar cold viruses https://www.dailymail.co.uk/news/art...-Covid-19.html | | | | | A German study found that while T-cell memory exists, the immune reaction is unfortunately not very effective against Covid. https://www.medrxiv.org/content/10.1....15.20188896v1
"Key points
- Pre-existing SARS-CoV-2-reactive memory T cells are present in all humans, but have low functional avidity and broad target specificities
- Pre-existing memory T cells show only marginal cross-reactivity to common cold corona viruses
- Frequencies of pre-existing memory T cells increase with the size of the CD4+ memory compartment reflecting the “immunological age” of the individual
- Low-avidity and polyclonal, but strongly enhanced SARS-CoV-2 specific T cell responses develop in severe COVID-19, suggesting their origin from pre-existing memory
- The immunological age may represent a risk factor to develop severe COVID-19"
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24.11.2020, 14:03
| Member | | Join Date: Jul 2019 Location: Vaud
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| | Re: Coronavirus | Quote: | |  | | | I have the feeling that the RNA based vaccines (Pfizer / Moderna) are likely to be safer than the traditional type vaccines. | | | | |
I am a biologist who works with level 2 viruses and knows quite a bit about virus biology and molecular biology. They are the new kid in town, but I think mRNA vaccines are likely to be very safe and probably the way of the future. They seem like an excellent way to deliver a high amount of antigen with a low chance of long-term side effects. I am less enthusiastic about DNA based vaccines. Reason being that mRNA molecules can directly drive high-level expression of antigen proteins, but they don't stick around in the body for long. DNA molecules can hang around for years, and there is always the risk of it integrating into your genome.
Last edited by bossie; 24.11.2020 at 14:16.
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24.11.2020, 14:03
|  | Forum Legend | | Join Date: Jan 2010 Location: Neuchâtel
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| | Re: Coronavirus | Quote: | |  | | | Let's see if the EF scientists agree | | | | | As a real scientist I have to say that is actually quite likely.
It has been known from pretty early on that T cells are important in combatting COVID-19.
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24.11.2020, 15:01
| Forum Legend | | Join Date: Mar 2013 Location: Formerly in Neuchatel
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| | Re: Coronavirus | Quote: | |  | | | I just didn't see your post till now! Very good!  | | | | | Just felt my stolen joke should get the thanks it deserved | The following 3 users would like to thank porsch1909 for this useful post: | | 
24.11.2020, 15:29
| Banned | | Join Date: Oct 2020 Location: Basel
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| | Re: Coronavirus
Does science know:
1. Why some virus infections cause lifelong immunity and others do not?
2. Why some antiviral vaccines provide lifelong resistance to infection and others barely effective for 6 months?
3. Why cross immunity does not exist to seasonal flu viruses?
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24.11.2020, 15:53
| Forum Veteran | | Join Date: Apr 2012 Location: Bern
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| | Re: Coronavirus
Seems Switzerland can't give us a solid answer as to when we will get the vaccines, stating early 2021 is most likely.
Anyone have insight as to why a country with many pharmaceutical powers cannot get a vaccine before France? FFS | The following 2 users would like to thank Susie-Q for this useful post: | | 
24.11.2020, 16:01
| Forum Veteran | | Join Date: Oct 2017 Location: ZH
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| | Re: Coronavirus | Quote: | |  | | | Seems Switzerland can't give us a solid answer as to when we will get the vaccines, stating early 2021 is most likely.
Anyone have insight as to why a country with many pharmaceutical powers cannot get a vaccine before France? FFS  | | | | | Profit?
Waiting for them to be tested en masse on the French?
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24.11.2020, 16:01
| Forum Veteran | | Join Date: Sep 2020 Location: LaCote
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| | Re: Coronavirus | Quote: | |  | | | Seems Switzerland can't give us a solid answer as to when we will get the vaccines, stating early 2021 is most likely.
Anyone have insight as to why a country with many pharmaceutical powers cannot get a vaccine before France? FFS  | | | | | "Swissmedic spokesman Lukas Jaggi explains: Only when the entire documentation and the clinical part have been submitted and evaluated can a decision on an initial authorization be made. "We hope to receive more meaningful data from approval studies at the beginning of 2021 and are preparing to be able to make a decision quickly." https://www.watson.ch/schweiz/wissen...in-der-schweiz | The following 2 users would like to thank Sigh for this useful post: | | 
24.11.2020, 16:07
|  | Forum Legend | | Join Date: Mar 2008 Location: Wallis
Posts: 4,849
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| | Re: Coronavirus | Quote: | |  | | | "Swissmedic spokesman Lukas Jaggi explains: Only when the entire documentation and the clinical part have been submitted and evaluated can a decision on an initial authorization be made. "We hope to receive more meaningful data from approval studies at the beginning of 2021 and are preparing to be able to make a decision quickly." https://www.watson.ch/schweiz/wissen...in-der-schweiz | | | | | Yet the UK, USA and Germany will have it done in December | This user would like to thank Island Monkey for this useful post: | | 
24.11.2020, 16:40
| Banned | | Join Date: Oct 2020 Location: Basel
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| | Re: Coronavirus | Quote: | |  | | | Seems Switzerland can't give us a solid answer as to when we will get the vaccines, stating early 2021 is most likely.
Anyone have insight as to why a country with many pharmaceutical powers cannot get a vaccine before France? FFS  | | | | | I only have a guess: VP of Novartis believes Hydroxychloroquine cures Covid 19 , so vaccine might not be high priority as long as that genius is at the head.
| 
24.11.2020, 16:41
| Forum Veteran | | Join Date: Apr 2012 Location: Bern
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| | Re: Coronavirus | Quote: | |  | | | I only have a guess: VP of Novartis believes Hydroxychloroquine cures Covid 19 , so vaccine might not be high priority as long as that genius is at the head. | | | | | Are they still using this for treatment?
| 
24.11.2020, 16:44
|  | Forum Legend | | Join Date: Oct 2009 Location: Basel
Posts: 14,118
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| | Re: Coronavirus | Quote: | |  | | | I only have a guess: VP of Novartis believes Hydroxychloroquine cures Covid 19 , so vaccine might not be high priority as long as that genius is at the head. | | | | | guess again. novartis sold their vaccines business to GSK back in 2015.
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24.11.2020, 16:46
|  | Forum Legend | | Join Date: Apr 2010 Location: Verbier
Posts: 19,419
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| | Re: Coronavirus | Quote: | |  | | | guess again. novartis sold their vaccines business to GSK back in 2015. | | | | | Vaccines don't make much Monet according to an esteemed member, I guess it's a matter of timing.
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