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  #21  
Old 26.04.2020, 22:09
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Re: What do you think about the COVID-19 antibody tests?

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It will be interesting to see how SBB and local public transport companies handle opening up and social distancing.
I am not so sure they will do much. At the start of the crisis I had written to them asking what measures they would take and whether or not they would clean the trains more regularly. The answer was that they would only enforce that the attendants not touch the Swiss Pass. I read in the news that Italy demanded SBB clean their trains more if they were to enter Italy.
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  #22  
Old 27.04.2020, 19:38
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Re: What do you think about the COVID-19 antibody tests?

Tests are available and have been for a couple of weeks. One issue though is that antibodies seem to develope a bit later than expected so it is first now it makes sense to to test.

If test shows IgG you have had it (around 95-97% sensitivity). If it shows IgM a PCR test is recommended.

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I've been informed that the tests are not available yet. Is that still the case?
Also what happens if it turns out positive? Does that mean you had it? Or may still have it?
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  #23  
Old 27.04.2020, 19:40
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Re: What do you think about the COVID-19 antibody tests?

Not correct. There are rapid test with 93-97% sensitivity for IgG.

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Every single test has been unreliable so far, even the best ones from Roche have issues.

And the last thing I'd do is provide medical info to my employer, they have no business knowing or managing my health.
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Old 27.04.2020, 20:25
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Re: What do you think about the COVID-19 antibody tests?

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Not correct. There are rapid test with 93-97% sensitivity for IgG.
Yes correct.
93-97% sensitivity for IgG is a meaningless number without some kind of explanation. The devil is in the detail. This number suggests a 5% false negative -how do you decide what a false negative is?
False positives -not given and maybe the more important number.
Is 95% certainty good enough? People are going to be making important decisions based on these test results.
The proof as to how good tests are will be in the market place. Fortunately there is enough competition world-wide, but unfortunately this is all going to take time.
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Old 28.04.2020, 16:36
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Re: What do you think about the COVID-19 antibody tests?

Preliminary results from an ongoing study in Canton Geneva using antibody tests suggest that for every person who got tested positive, 4-5 have had the virus without anybody aware. For the Canton Bern (1733 test-positives and 1kk residents) those data imply mean that almost 1% in the Canton have had the virus so far.

Based on that, in a perfect world and ignoring potential time contraints to produce the antibodies, on average one out of 100 people from Bern should test positive, the other 99 should test negative.

Now, the antibody test
- sensitivity, the probability of correct positives, is unknown. Let's assume 99%
- specificity, the probability for false positives, is unknown. Let's assume 99%
I believe both values would be very good.

Those probabilities would mean that out of 100 Bern residents tested one would be correctly positve and one would be falsely positive.

A change in specificity sensitivity would have negligible effect, but lower specificity would make the probable outcome less attractive. For instance, specificity of 97% would mean that 3 out of 100 would falsely test positive vs one correct positive.

One remedy to that would be testing by two different tests. Maybe private labs do that on their own, no idea. (the PCR tests with a positive result performed by the hospitals do indeed get verified by one of the official reference labs).

Last edited by Urs Max; 29.04.2020 at 09:55. Reason: used the wrong word in the "A change" paragraph
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  #26  
Old 28.04.2020, 17:38
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Re: What do you think about the COVID-19 antibody tests?

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Did your GP refuse to test you or tell you to stay home? I would think given the symptoms and where you'd been that some doctor somewhere in CH would want to test you.
The unwritten policy is that you don't get tested unless you are in the risk group (old or medical condition) or you've already gotten very sick (hospitalization). A colleague of mine had all the symptoms and was sick for ca. 2 weeks with fever and cough etc., but did not get the test because he was not in the risk group (in the 40s, no medical condition).
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Old 07.05.2020, 16:08
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Re: What do you think about the COVID-19 antibody tests?

The new antibody test by Roche should change the landscape with its 100% sensitivity and 99.8% specificity. No idea when it'll be available but it may help to ask for this particular one.

Remember that supposedly the body takes 2-3 months to start producing the specific Covid-19 antibodies.
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