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Old 15.11.2021, 21:47
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Mix and match booster jabs?

Now that Switzerland is starter its booster jab program, is it possible to select a different vaccine for the booster than for the first two? Specifically, with two initial Pfizer jabs, is it possible to select Moderna as the booster?
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Old 15.11.2021, 22:05
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Re: Mix and match booster jabs?

Here in Neuchâtel they select people to have all 3 matching- Pfizer OR Moderna.

You really need to phone your local centre to get their answer, based on local info and decision (as per usual in CH).
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Old 15.11.2021, 23:20
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Re: Mix and match booster jabs?

I‘m having my booster this Friday and I wasn‘t really given a choice…neither did I ask for one. It seems that in kt Zurich the default is the same for all 3 shots. You can call the hotline though and see what they say.
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Old 16.11.2021, 09:04
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Re: Mix and match booster jabs?

I registered for my booster here in Fribourg canton yesterday and the questionnaire asked me which vaccines I'd had - Moderna - so I assume the booster will be the same.
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Old 16.11.2021, 09:20
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Re: Mix and match booster jabs?

For once, this is not a cantonal decision but it is the BAG/SwissMedic guideline to use the same vaccine as the first ones (whenever possible).
Personally, I would prefer a mix ... but the guidelines don't seem to support it (so far)
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Old 16.11.2021, 09:43
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Re: Mix and match booster jabs?

As far as I understand mixing the vaccines of similar type won't give you any benefit. So it's only reasonable if you want "stronger" or "weaker" vaccine in the sense of the amount of main component.

I'm very disappointed that Moderna also needs booster after 6 months. In this case I don't understand it's benefit at all. It's more expensive, causes more side effects and the risk-benefit ratio for people under 30 is under question. So what's the point of using it at all?
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Old 16.11.2021, 11:40
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Re: Mix and match booster jabs?

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As far as I understand mixing the vaccines of similar type won't give you any benefit. So it's only reasonable if you want "stronger" or "weaker" vaccine in the sense of the amount of main component.

I'm very disappointed that Moderna also needs booster after 6 months. In this case I don't understand it's benefit at all. It's more expensive, causes more side effects and the risk-benefit ratio for people under 30 is under question. So what's the point of using it at all?
So far it looks like the Moderna does not lose effectiveness as fast, but it's hard to tell as there are fewer studies of it. (Much of the world is going by the Israeli data at this point, which is about the BioNTech (aka Pfizer) vaccine.) But from a policy and communication standpoint, it is probably simpler to boost people regardless of what vaccine they received.
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Old 16.11.2021, 11:41
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Re: Mix and match booster jabs?

Annoyingly, canton AG says they don't plan to do boosters to anyone except over-65s...

Which makes me need to find the vaccine elsewhere, as it seems like more and more countries are starting to consider or ask for a booster...
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Old 16.11.2021, 11:47
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Re: Mix and match booster jabs?

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Annoyingly, canton AG says they don't plan to do boosters to anyone except over-65s...

Which makes me need to find the vaccine elsewhere, as it seems like more and more countries are starting to consider or ask for a booster...
In VD the require that you prove you live in Vaud, or work for a Vaud based health provider.

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Le jour du rendez-vous, prenez bien :
- votre carte d'identité
- votre carte d'assuré
- votre carnet de vaccination
- et un document qui atteste que vous résidez bien dans le canton (par exemple une facture des Services Industriels) ou un justificatif de travail dans un hôpital ou une institution communautaire vaudoise (par exemple badge, attestation employeur, etc.).
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Old 16.11.2021, 11:49
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Re: Mix and match booster jabs?

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As far as I understand mixing the vaccines of similar type won't give you any benefit. So it's only reasonable if you want "stronger" or "weaker" vaccine in the sense of the amount of main component.

I'm very disappointed that Moderna also needs booster after 6 months. In this case I don't understand it's benefit at all. It's more expensive, causes more side effects and the risk-benefit ratio for people under 30 is under question. So what's the point of using it at all?
There is some benefit if you are in an older age group.



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Annoyingly, canton AG says they don't plan to do boosters to anyone except over-65s...

Which makes me need to find the vaccine elsewhere, as it seems like more and more countries are starting to consider or ask for a booster...

They’ll probably open up the booster to other age groups, but I wish they’d do it before the holidays when people are more likely to travel, if they can. Zurich is not offering it to under 65s at the moment either.
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Old 16.11.2021, 11:53
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Re: Mix and match booster jabs?

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Annoyingly, canton AG says they don't plan to do boosters to anyone except over-65s...

Which makes me need to find the vaccine elsewhere, as it seems like more and more countries are starting to consider or ask for a booster...

It will be a federal decision, and I suspect it will eventually be made available to everyone >6 months on. I would think starting in December? That's what most other rich countries are doing, Switzerland will probably go this way too, especially after the Covid law vote.
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Old 16.11.2021, 11:55
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Re: Mix and match booster jabs?

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Annoyingly, canton AG says they don't plan to do boosters to anyone except over-65s...

Which makes me need to find the vaccine elsewhere, as it seems like more and more countries are starting to consider or ask for a booster...
Same here. But I expect this to changes the moment Swissmedic (?) recommends boosters for all. There was talk of this being announces some time this week, but it has not been announced.

From what I remember the only proven benefit of mix and match was AZ and Biontech (for second jab). So I don't know why one would want to mix and match.
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Old 16.11.2021, 14:07
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Re: Mix and match booster jabs?

In my case I've had 2 Moderna jabs with such strong side-effects (useless arm, fever, chills, shakes, severe nausea lasting 3 days plus one to recover) so I'd like to change to Pfizer for the booster since the side effects appear to be a bit milder. For effectiveness, I haven't found any evidence either that there's a benefit in mixing two mRNA vaccines. So in the case of 2 Pfizers, I guess there's no motivation to bet a Moderna booster (my original question).
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Old 16.11.2021, 14:13
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Re: Mix and match booster jabs?

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In my case I've had 2 Moderna jabs with such strong side-effects (useless arm, fever, chills, shakes, severe nausea lasting 3 days plus one to recover) so I'd like to change to Pfizer for the booster since the side effects appear to be a bit milder. For effectiveness, I haven't found any evidence either that there's a benefit in mixing two mRNA vaccines. So in the case of 2 Pfizers, I guess there's no motivation to bet a Moderna booster (my original question).
Extreme side effects from Moderna could be considered a good enough reason to request a different vaccine for the booster.
I don’t know what they consider as serious side effects though.


I know somebody who had a serious reaction to the first Moderna and recently had the Johnson and Johnson vaccine as their second dose.
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Old 23.11.2021, 23:51
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Re: Mix and match booster jabs?

Anyone heard any talk in the media about CH's plans or ability to provide 1/2 dose Moderna boosters?

This is already approved, planned, and I believe may even already started in the US.

Moderna provided studies and the FDA/CDC approved this saying that this amount is proven effective as a booster with less side effects than the original full dose.

I'm wondering if CH has said anything about gearing up and adjust to provide the 1/2 dose.
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Old 23.11.2021, 23:58
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Re: Mix and match booster jabs?

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Anyone heard any talk in the media about CH's plans or ability to provide 1/2 dose Moderna boosters?

This is already approved, planned, and I believe may even already started in the US.

Moderna provided studies and the FDA/CDC approved this saying that this amount is proven effective as a booster with less side effects than the original full dose.

I'm wondering if CH has said anything about gearing up and adjust to provide the 1/2 dose.
No, haven‘t. Do you have a reliable link?
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Old 24.11.2021, 00:08
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Re: Mix and match booster jabs?

Yes the Moderna booster is only half-dose, always has been.
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Old 24.11.2021, 00:09
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Re: Mix and match booster jabs?

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Yes the Moderna booster is only half-dose, always has been AFAIK. https://www.swissmedic.ch/swissmedic...r-impfung.html
And the Pfizer?
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Old 24.11.2021, 00:18
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Re: Mix and match booster jabs?

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And the Pfizer?
no same dose as far as I understand, I was trying to link the actual information but the page does not have a working link.
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Old 24.11.2021, 11:57
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Re: Mix and match booster jabs?

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Yes the Moderna booster is only half-dose, always has been.
What do you mean by "always has been"?

Do you mean that since they started giving moderna boosters to elderly it has always been 1/2 the dose of the original moderna vaccine they would have received 6 months prior?
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