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  #21  
Old 09.05.2017, 14:57
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Re: Marijuana reverses aging?

Just waiting for acmilan to post some spliffy cake recipes

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Old 09.05.2017, 15:32
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Re: Marijuana reverses aging?

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My Wife and I (and our dog), used Golden Paste last year. We stopped as it was inconvenient to take it 2x/day due to the taste. Not that it tastes horrible, but we never found an easy way to eat/drink it regularly.

Making it ourselves, meant it was a challenge to put it into capsules. Any tips?
Make a drink with it - heat whole milk+turmeric+honey/sweetener of choice; stir before you take sips, as the turmeric settles fast, and it feels silty by the time you finish your drink.
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  #23  
Old 09.05.2017, 15:38
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Re: Marijuana reverses aging?

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Just waiting for acmilan to post some spliffy cake recipes

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I prefer Brownies though
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Old 09.05.2017, 15:44
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Re: Marijuana reverses aging?

Interesting article in Scientific American about cannabis.

https://www.scientificamerican.com/a...ks-for-users1/

Some have long said that there is a link between cannabis use and schizophrenia and between cannabis use and psychosis. Others point out that though there is a correlation, no causality can be inferred, and that there could be other determining factors.

The THC levels in cannibis are, generally, increasing severalfold. This is at least part of the explanation of why users report feeling knocked over, now, by just a little use, but remember a far milder, gentler experience when they used cannabis years ago.

Much evidence shows that users of low-THC cannabis are benefiting from medicinal advantages such as pain relief, relaxation, etc., while there seem to be increasing reports that those who use high-THC cannabis (especially if they are young, and/or are new to using cannabis regularly) are probably at a significantly higher risk of experiencing psychosis, even when not using.

Whether or not this is the case, however, is hard to monitor and test, as many users do not know, and cannot test, the products they buy.
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Old 09.05.2017, 15:55
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Re: Marijuana reverses aging?

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Making it ourselves, meant it was a challenge to put it into capsules. Any tips?
Most Indians eat curry with Turmeric, about 1/4 teaspoon per person per meal.

But we are now off topic, can we get back to Marijuana ?
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Old 09.05.2017, 15:55
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Re: Marijuana reverses aging?

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Recently went to a Conference by Prof Kurt Hostettmann, who teaches pharmacology at Geneva, Lausanne, and China- and he claims that Cucurma, according to recent trials, seems to be the best way to slow down dementia and Alzheimers (as well as being a great anti-imflammatory) - and without side effects.
I would take the so-called health benefits of Turmeric with a healthy side-order of skepticism until proper studies have been carried out. Just because one professor makes claims about it, doesn't make it true. Linus Pauling perpetuated the theory that large doses of Vitamin C could combat the common cold, which has since been disproved. A patient in the US also recently died after IV infusion with turmeric administered by a "naturopath".
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  #27  
Old 09.05.2017, 16:09
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Re: Marijuana reverses aging?

Sorry for the threadjack...

One thing that amazes me is the almost worldwide avoidance of funding clinical studies of the efficacy of cannabinoids for a variety of conditions. Maybe a connection to aging will make it more palatable to gov't. I understand the economics of Big Pharma and why it/they might be reluctant, but what about gov't. Canada has been very much against medical cannabis (Google Rick Simpson Oil), so will be interesting to see what happens under Trudeau.

I mentioned the other day that while I have no desire to use cannabis recreationally, I am 110% in favor of looking into its medical efficacy.

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Most Indians eat curry with Turmeric, about 1/4 teaspoon per person per meal.

But we are now off topic, can we get back to Marijuana ?
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Old 09.05.2017, 16:15
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Re: Marijuana reverses aging?

But do they sell legal weed in Switzerland?
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Old 09.05.2017, 16:32
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Re: Marijuana reverses aging?

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Sorry for the threadjack...

One thing that amazes me is the almost worldwide avoidance of funding clinical studies of the efficacy of cannabinoids for a variety of conditions. Maybe a connection to aging will make it more palatable to gov't. I understand the economics of Big Pharma and why it/they might be reluctant, but what about gov't. Canada has been very much against medical cannabis (Google Rick Simpson Oil), so will be interesting to see what happens under Trudeau.

.
Perhaps they haven't got that far. To my (limited ) knowledge, clinical trials aren't really conducted in the way that you're suggesting:- 'Give some patients a drug and see what happens...'


It's normally - we've seen this drug have this effect on this condition in the lab, on animals and so on - let's develop a drug to treat this condition and move onto clinical trials.

Of course, clinical trials do show side effects that may be beneficial but were not planned (sildenafil citrate AKA Viagra, for example).

Cannabinoids do get investigated for theraputic effects:

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Lab research

Virtually all the scientific research investigating whether cannabinoids can treat cancer has been done using cancer cells grown in the lab or animal models. It’s important to be cautious when extrapolating these results up to real live patients, who tend to be a lot more complex than a Petri dish or a mouse.

A researcher with some cells in a Petri dish
Virtually all the research into cannabinoids and cancer so far has been done in the lab.

Through many detailed experiments, handily summarised in this recent article in the journal Nature Reviews Cancer, scientists have discovered that various cannabinoids (both natural and synthetic) have a wide range of effects in the lab, including:

Triggering cell death, through a mechanism called apoptosis
Stopping cells from dividing
Preventing new blood vessels from growing into tumours
Reducing the chances of cancer cells spreading through the body, by stopping cells from moving or invading neighbouring tissue
Speeding up the cell’s internal ‘waste disposal machine’ – a process known as autophagy – which can lead to cell death
All these effects are thought to be caused by cannabinoids locking onto the CB1 and CB2 cannabinoid receptors. It also looks like cannabinoids can exert effects on cancer cells that don’t involve cannabinoid receptors, although it isn’t yet clear exactly what’s going on there.
So far, the best results in the lab or animal models have come from using a combination of highly purified THC and cannabidiol (CBD), a cannabinoid found in cannabis plants that counteracts the psychoactive effects of THC. But researchers have also found positive results using synthetic cannabinoids, such as a molecule called JWH-133.

It’s not all good news though, as there’s also evidence that cannabinoids may also have undesirable effects on cancer.

For example, some researchers have found that although high doses of THC can kill cancer cells, they also harm crucial blood vessel cells, although this may help their anti-cancer effect by preventing blood vessels growing into a tumour. And under some circumstances, cannabinoids can actually encourage cancer cells to grow, or have different effects depending on the dosage and levels of cannabinoid receptors present on the cancer cells. [Edited for clarity and to add reference – KA 27/07/12]
Source
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Old 09.05.2017, 16:39
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Re: Marijuana reverses aging?

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Sorry for the threadjack...

Canada has been very much against medical cannabis (Google Rick Simpson Oil), so will be interesting to see what happens under Trudeau.
.
Maybe because it would be better labelled Rick Simpson's snake oil for it's effiencency.

There are institutes looking into it but even the ones that are the most far along say they are, at the best, several decades away from having anything tangible along the lines of curing cancer.
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Old 09.05.2017, 16:48
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Re: Marijuana reverses aging?

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But do they sell legal weed in Switzerland?

Apparently yes.

Although noone seems to know where:

https://www.englishforum.ch/daily-li...id-happen.html

cheers
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Old 09.05.2017, 16:58
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Re: Marijuana reverses aging?

Maybe I was not clear, but I was not suggesting that they feed patients cannabinoids and monitor what happens. When I mentioned "a variety of conditions" my intent was to point out that I don't understand why cannabis has not been studied specifically for pain management or wrt cancer fighting properties. There seems to be plenty of anecdotal evidence pointing to these two examples, for instance.


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Perhaps they haven't got that far. To my (limited ) knowledge, clinical trials aren't really conducted in the way that you're suggesting:- 'Give some patients a drug and see what happens...'


It's normally - we've seen this drug have this effect on this condition in the lab, on animals and so on - let's develop a drug to treat this condition and move onto clinical trials.

Of course, clinical trials do show side effects that may be beneficial but were not planned (sildenafil citrate AKA Viagra, for example).

Cannabinoids do get investigated for theraputic effects:



Source
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  #33  
Old 09.05.2017, 16:59
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Re: Marijuana reverses aging?

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Apparently yes.

Although noone seems to know where:

https://www.englishforum.ch/daily-li...id-happen.html

cheers
SC

The latest I heard was that in the city of Bern some pharmacies will sell it soon as a trial. But must admit I can't remember where I read that and can not vouch for its truth content.

I have actually given up, smoking1 and smoking2 almost three years ago, but when Daughter#1 and her boyfriend are here, I am allowed to have a drag or two, for old times' sake

Get some seeds and grow your own.
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  #34  
Old 09.05.2017, 17:14
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Re: Marijuana reverses aging?

I do not know a lot about Rick Simpson, but I believe that he posts all of his info on YouTube and does not sell anything. In fact, I think he has even given away quantities of oil to people who can't afford it.

In any case, there is a lot of info out there. I stumbled across it a few years ago when my dog had hemangiosarcoma. We made our own oil and it seemed to help stimulate our dog's appetite, when she was mostly refusing to eat. I can't vouch for any cancer fighting properties as the disease took her in 6 weeks.

One thing it did was open my eyes to possibilities that I did not know about before. And because I do believe in some conspiracy theories, it does not surprise me that Big Pharma seems to be behind a lot of the anti-cannabis news. It also seems that were cannabis to be discovered today, in a rainforest somewhere, it would probably be hailed as a wonder plant.

And I have never been a user, lest you question my motives. It puts me to sleep, so I stick to red wine! So why is Spain (where I live now) one of the only countries that has done any study? Seems odd...


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Maybe because it would be better labelled Rick Simpson's snake oil for it's effiencency.

There are institutes looking into it but even the ones that are the most far along say they are, at the best, several decades away from having anything tangible along the lines of curing cancer.
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Old 09.05.2017, 17:23
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Re: Marijuana reverses aging?

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But do they sell legal weed in Switzerland?
YES legal. Low THC cannabis is legal (<1%THC). Has been for 5 years. Google it or see this reuters article.

REASONING: Switzerland has a harm minimization stance on drugs.

KEY: What no one mentions in the thread so far is there are basically two active ingredients - one is therapeutic (CBD or Cannabidiol) and ones makes you high/impaired (THC). You get these two ingredients in different ratios. While recreational strains have been for higher THC (for the euphoria), turns out CBD has an important role in mediating the negative effects of THC, and is responsible for the therapeutic effects besides.

Obviously lots of claims on the 'good' effects of CBD, and the two with most commonly approved medical uses (where there is solid medical evidence and hence approved by governments) for:
1. neuropathic pain (when it isn't responding well to usual painkillers and opiates, or they aren't well tolerated).. I guess all many kinds of persistence nerve pain goes in this bucket.
2. chemo-induced nausea and vomiting. (stops you feeling sick and the "munchies", or love of food sensations, brings back apetite)

OH, and importantly, pure CBD shows no dependence or withdrawal syndrome from short term use, ***unlike opiods*** (see US epidemic on that).

Also CBD stops extreme childhood epilepsy for which there is no other effective treatment. And many more medical uses uses (use Google Scholar) .
So, I speak of the CBD positive effects. there are side effects like dry mouth and possibly drowsiness.

I am not aware of claims that THC is much good for you (and besides the pleasant euphoria at low doses, it gives you short term memory loss, paranoia, psychotic thinking, time dilation, poor depth perception, etc and for me, depression for about 3 days, so to me that is NOT attractive )

YES available 'retail'. available in shops now in Zurich. Kiosks Tobacconist etc. I found some for sale in a shop in Zurich, so looked it up and was surprised to find it became legal 5 years ago.

YES still potential issues with law enforcement if stopped with it, as you need to be able to prove its low THC and not the potent street stuff. In practice cops may just confiscate/fine for small quantity, but if you insist on challenging them to get it tested, they will, but if its >1%THC you need to pay the testing bill and fees.

YES expensive, for what you get (chf28 for tin with 1.5 grams of low potency head), but then again, its Switzerland, and you're presumably getting tested, bio, low THC /high CBD stuff with known provenance. And its taxed, yay! liquids and other extracts available from pro shops...

NO I haven't tried it. But the obvious appeal (as mentioned by those above) is to be able to enjoy the relaxing and therapeutic effects without feeling like you have been kicked in the head from having one tiny puff of the modern high potency skunk weed. Indeed, a niche is we older folks, who would like to have a mellow low potency time, like in our youth when it grew 'wild' in our backyards, without the downside. I would like to hear what that is like, especially for back pain and arthritis!

TIP: apparently best to avoid alcohol (a CNS depressant), and just have it on its own. you will be better able to isolate the effects too (and hopefully report back here).

ALSO, kiddies reading, wait until you're around 25 to play around with stuff like this recreationally, as neurochemistry is a delicate thing. Your brain is still developing till around 21-25, so best wait till then before you impair it. I know too many people who have reacted badly, and schizophrenia has no cure.
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Old 09.05.2017, 19:21
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Re: Marijuana reverses aging?

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And the same article mentions the 'well-established' link between cannabis use and both lowered intelligence and psychotic disorders in younger people.
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Where is that, I can't find it in the link.
Sorry, my 'well-established' was a misquote, should have been 'well-known' , but there's plenty else in the text that supports it.

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The discovery has raised hopes for a treatment that improves brain function in old age without inducing the behavioural effects well known to recreational users of the drug.
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Research on cannabis use by adolescents has found compelling evidence that regular, heavy use can impair the memory.
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The performance of the younger mice plummeted on THC,
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  #37  
Old 09.05.2017, 19:34
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Re: Marijuana reverses aging?

Well I was just a little confused, since it also didn't mention anything about psychosis or intelligence.
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Old 09.05.2017, 19:52
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Re: Marijuana reverses aging?

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Also CBD stops extreme childhood epilepsy for which there is no other effective treatment. And many more medical uses uses (use Google Scholar)

I am not aware of claims that THC is much good for you (and besides the pleasant euphoria at low doses, it gives you short term memory loss, paranoia, psychotic thinking, time dilation, poor depth perception, etc and for me, depression for about 3 days, so to me that is NOT attractive )
Not sure whether it's the CBD or totally unrelated but I've witnessed someone who had childhood epilepsy, but who had not had a seizure for ten years, have a bad one after smoking hash for the first time.
Unfortunately they were standing on a concrete plinth and hit their head on it when they collapsed.

I've also seen someone a week or so after they tried to commit harikiri with a sword after heavy smoking.

And the number of cases of severe psychosis I've seen after smoking. (involving the Police) are many.

Of course I cannot say, in any of these cases, that THC was the cause but I can rule out alcohol in all of them.

But hey, do what you want to your own bodies but why do you expect someone else to sort out the mess afterwards?
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Old 09.05.2017, 21:13
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Re: Marijuana reverses aging?

I swear to high I'm not God, but seriously, stay in drugs, eat school, and don't do vegetables.
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Old 09.05.2017, 21:57
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Re: Marijuana reverses ageing?

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Sorry, my 'well-established' was a misquote, should have been 'well-known' , but there's plenty else in the text that supports it.
Certainly there are strong links between use of this drug by young people and certain conditions.

The discussion here is "can Marijuana help old people reverses ageing"? So we are talking about old people not young people.

Now we fall into the well known doctor's dilemma; which is worse, the cure or the disease?

For example, chemotherapy for cancer.
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